STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD30949.1Conserved hypothetical protein. (333 aa)    
Predicted Functional Partners:
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
 0.996
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.925
sbnB
Ornithine cyclodeaminase, putative; Catalyzes the hydrolysis of N-((2S)-2-amino-2-carboxyethyl)- L-glutamate (ACEGA) to form L-2,3-diaminopropionic acid and 2- oxoglutarate. Involved in the biosynthesis of L-2,3-diaminopropionic acid (L-Dap), a precursor of staphyloferrin B and antibiotics. Belongs to the ornithine cyclodeaminase/mu-crystallin family.
  
 
 0.915
ABD29594.1
Glutamate synthase, large subunit, putative.
   
 
 0.897
ABD31394.1
Aldehyde dehydrogenase, putative.
 
 0.808
ABD31928.1
Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.747
ABD30947.1
Conserved hypothetical protein.
   
  0.698
pxpA
Conserved hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
   
 
  0.660
ABD29463.1
Conserved hypothetical protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.649
putP
Proline uptake protein; Catalyzes the sodium-dependent uptake of extracellular L- proline (By similarity). Since most S.aureus strains are L-proline auxotrophs, this transporter may aid the bacterial persistence during an infection of tissues with low proline concentrations; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.649
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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