Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arsCArsenate reductase; Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. (131 aa)    
Predicted Functional Partners:
ABD30955.1
Arsenate operon regulator.
 
  
 0.976
trxA
Thioredoxin; Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
   
 
 0.918
ABD30956.1
Arsenical pump membrane protein subfamily; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.
 
  
 0.863
ABD29225.1
Conserved hypothetical protein.
  
   0.731
ABD31306.1
Sucrose-6-phosphate dehydrogenase, putative; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
  
   0.539
tpx
Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
      
 0.511
ABD30926.1
Conserved hypothetical protein.
   
   0.431
ABD31846.1
Conserved hypothetical protein.
   
   0.431
ABD29224.1
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
 
 
   0.411
ABD30953.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.406
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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