STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31057.1Conserved hypothetical protein. (347 aa)    
Predicted Functional Partners:
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
      0.889
ABD30063.1
Conserved hypothetical protein.
  
     0.687
hemL2
Glutamate-1-semialdehyde-2,1-aminomutase, putative.
       0.687
ABD31054.1
Conserved hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.638
ABD31055.1
Conserved hypothetical protein.
       0.638
ABD29892.1
Conserved hypothetical protein.
      
 0.613
ABD30218.1
Succinate dehydrogenase, flavoprotein chain TC0881, putative.
      
 0.613
ABD30453.1
Conserved hypothetical protein.
     
 0.613
ABD29205.1
Conserved hypothetical protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
      
 0.611
ABD30066.1
Conserved hypothetical protein; Belongs to the UPF0738 family.
  
     0.607
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.