STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31100.1Phage portal protein, SPP1 family. (511 aa)    
Predicted Functional Partners:
ABD31101.1
Phage terminase, large subunit, PBSX family.
 
  
 0.968
ABD31099.1
Phage putative head morphogenesis protein, SPP1 gp7 family domain protein.
 
     0.964
ABD31102.1
Terminase small subunit, putative.
 
    0.948
ABD31094.1
Phi Mu50B-like protein.
 
    0.867
ABD31096.1
Phage head protein, putative.
 
     0.856
ABD31097.1
Conserved hypothetical phage protein.
 
    0.831
ABD31090.1
Phage structural protein, putative.
 
   
 0.790
ABD31290.1
Phage terminase, small subunit, putative.
 
    0.734
ABD30395.1
Conserved hypothetical protein.
 
    0.711
spa
Protein A; Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteoge [...]
  
 
 0.637
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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