STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptpAConserved hypothetical protein; Secreted tyrosine phosphatase that plays a critical role during infection as a bacterial effector protein that counteracts host defenses. Required for intramacrophage survival. (154 aa)    
Predicted Functional Partners:
ptpB
Conserved hypothetical protein; Dephosphorylates the phosphotyrosine-containing proteins. Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
 
0.899
ABD31146.1
Conserved hypothetical protein.
       0.856
ABD29225.1
Conserved hypothetical protein.
   
   0.777
ABD31143.1
Aminopeptidase PepS, putative.
       0.746
ABD31144.1
Conserved hypothetical protein; Belongs to the UPF0435 family.
       0.746
ABD31147.1
Conserved hypothetical protein; Belongs to the UPF0761 family.
  
  
 0.722
ABD29297.1
Capsular polysaccharide synthesis enzyme Cap8C.
     
 0.656
ABD31985.1
Capsular polysaccharide biosynthesis protein, Cap5C.
     
 0.656
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
     
 0.630
ABD29887.1
Conserved hypothetical protein.
   
   0.619
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.