STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
sdcSSodium-dependent transporter (huNaDC-1), putative; Mediates the transport of the dicarboxylates fumarate, malate, and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (520 aa)    
Predicted Functional Partners:
ABD31186.1
Conserved hypothetical protein.
       0.667
mnhA2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
  
  
 0.494
putP
Proline uptake protein; Catalyzes the sodium-dependent uptake of extracellular L- proline (By similarity). Since most S.aureus strains are L-proline auxotrophs, this transporter may aid the bacterial persistence during an infection of tissues with low proline concentrations; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.458
mnhE2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
      
 0.455
mnhB2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
   
  
 0.449
mnhD2
Conserved hypothetical protein; Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
   
  
 0.422
glcB
PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).
   
  
 0.413
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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