Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Experiments
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[Homology]
Score
ABD31186.1Conserved hypothetical protein. (365 aa)    
Predicted Functional Partners:
tcaA
Conserved hypothetical protein; Plays a major role in decreasing resistance to glycopeptide antibiotics; Belongs to the TcaA family.
  
     0.769
ABD30116.1
Transcriptional regulator, MarR family, putative.
  
     0.764
ABD31815.1
Conserved hypothetical protein.
  
     0.762
ABD31816.1
Conserved hypothetical protein.
  
     0.762
ABD30318.1
Conserved hypothetical protein.
  
     0.749
ABD31535.1
Conserved hypothetical protein.
  
     0.736
ABD31538.1
Conserved hypothetical protein.
  
     0.719
ABD29823.1
Conserved hypothetical protein.
  
     0.690
graX
Conserved hypothetical protein; Plays a role in resistance against cationic antimicrobial peptides (CAMPs). Facilitates the activation of GraS to transduce the signal to GraR.
  
    0.678
atl
Bifunctional autolysin precursor, putative; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolas [...]
  
     0.675
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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