STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31192.1Conserved hypothetical protein. (133 aa)    
Predicted Functional Partners:
ABD29814.1
Major facilitator superfamily protein superfamily.
  
     0.758
ABD29811.1
Conserved hypothetical protein.
  
     0.738
ABD30827.1
Conserved hypothetical protein.
  
     0.719
ABD30851.1
Conserved hypothetical protein.
  
     0.717
ezrA
Conserved hypothetical protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.714
ABD30148.1
Conserved hypothetical protein.
  
     0.713
ABD31401.1
Conserved hypothetical protein.
  
     0.710
ABD29913.1
Conserved hypothetical protein.
  
     0.699
femA
Methicillin resistance factor, FemA, putative; Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. Adds glycines 2 and 3 of the pentaglycine bridge, using glycyl-tRNA(Gly) as donor. Involved in resistance to methicillin.
  
     0.692
graX
Conserved hypothetical protein; Plays a role in resistance against cationic antimicrobial peptides (CAMPs). Facilitates the activation of GraS to transduce the signal to GraR.
  
     0.685
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.