STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31296.1Conserved hypothetical protein. (419 aa)    
Predicted Functional Partners:
spa
Protein A; Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteoge [...]
  
 
 0.810
ABD30938.1
Conserved hypothetical protein.
 
 
 0.777
tagX
tagX protein, putative; Belongs to the glycosyltransferase 2 family.
  
     0.767
tcaA
Conserved hypothetical protein; Plays a major role in decreasing resistance to glycopeptide antibiotics; Belongs to the TcaA family.
  
     0.767
ABD30116.1
Transcriptional regulator, MarR family, putative.
  
    0.765
ABD30920.1
Conserved hypothetical protein.
  
     0.765
ABD31195.1
Conserved hypothetical protein.
  
     0.765
ABD31433.1
Conserved hypothetical protein.
  
 0.764
ABD31535.1
Conserved hypothetical protein.
  
     0.764
ABD29816.1
Conserved hypothetical protein.
  
     0.752
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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