Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rexConserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (211 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.896
ABD29374.1
Conserved hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.713
ABD31312.1
ABC transporter, ATP-binding protein, putative.
       0.666
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
  
  
 0.607
ABD29294.1
Alcohol dehydrogenase, iron-containing, putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.575
pflB
Formate acetyltransferase; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
      
 0.538
codY
Conserved hypothetical protein; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
   
  
 0.521
ABD30905.1
1-acyl-sn-glycerol-3-phosphate acyltransferases domain protein.
  
   
 0.520
ABD30526.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
      
 0.504
rpsP
Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
    0.487
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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