| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABD30419.1 | ABD31321.1 | SAOUHSC_01321 | SAOUHSC_02283 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Conserved hypothetical protein. | 0.584 |
| ABD30419.1 | ilvA | SAOUHSC_01321 | SAOUHSC_02289 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Thereonine dehydratase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | 0.931 |
| ABD30419.1 | ilvC | SAOUHSC_01321 | SAOUHSC_02284 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.592 |
| ABD30419.1 | ilvD | SAOUHSC_01321 | SAOUHSC_02281 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.477 |
| ABD30419.1 | leuB | SAOUHSC_01321 | SAOUHSC_02286 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.404 |
| ABD30419.1 | leuD | SAOUHSC_01321 | SAOUHSC_02288 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.729 |
| ABD30419.1 | tdcB | SAOUHSC_01321 | SAOUHSC_01451 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). Belongs to the serine/thre [...] | 0.931 |
| ABD31320.1 | ABD31321.1 | SAOUHSC_02282 | SAOUHSC_02283 | Acetolactate synthase, large subunit, biosynthetic type. | Conserved hypothetical protein. | 0.999 |
| ABD31320.1 | ABD31488.1 | SAOUHSC_02282 | SAOUHSC_02468 | Acetolactate synthase, large subunit, biosynthetic type. | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | 0.921 |
| ABD31320.1 | ilvA | SAOUHSC_02282 | SAOUHSC_02289 | Acetolactate synthase, large subunit, biosynthetic type. | Thereonine dehydratase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | 0.985 |
| ABD31320.1 | ilvC | SAOUHSC_02282 | SAOUHSC_02284 | Acetolactate synthase, large subunit, biosynthetic type. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
| ABD31320.1 | ilvD | SAOUHSC_02282 | SAOUHSC_02281 | Acetolactate synthase, large subunit, biosynthetic type. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.993 |
| ABD31320.1 | leuB | SAOUHSC_02282 | SAOUHSC_02286 | Acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.994 |
| ABD31320.1 | leuD | SAOUHSC_02282 | SAOUHSC_02288 | Acetolactate synthase, large subunit, biosynthetic type. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.911 |
| ABD31320.1 | tdcB | SAOUHSC_02282 | SAOUHSC_01451 | Acetolactate synthase, large subunit, biosynthetic type. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). Belongs to the serine/thre [...] | 0.931 |
| ABD31321.1 | ABD30419.1 | SAOUHSC_02283 | SAOUHSC_01321 | Conserved hypothetical protein. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.584 |
| ABD31321.1 | ABD31320.1 | SAOUHSC_02283 | SAOUHSC_02282 | Conserved hypothetical protein. | Acetolactate synthase, large subunit, biosynthetic type. | 0.999 |
| ABD31321.1 | ABD31488.1 | SAOUHSC_02283 | SAOUHSC_02468 | Conserved hypothetical protein. | Acetolactate synthase, putative; Belongs to the TPP enzyme family. | 0.988 |
| ABD31321.1 | ilvA | SAOUHSC_02283 | SAOUHSC_02289 | Conserved hypothetical protein. | Thereonine dehydratase, putative; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | 0.986 |
| ABD31321.1 | ilvC | SAOUHSC_02283 | SAOUHSC_02284 | Conserved hypothetical protein. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
