| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABD29709.1 | ABD31559.1 | SAOUHSC_00562 | SAOUHSC_02545 | Phosphomethylpyrimidine kinase. | Conserved hypothetical protein. | 0.526 |
| ABD29709.1 | tenA | SAOUHSC_00562 | SAOUHSC_02331 | Phosphomethylpyrimidine kinase. | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity may not be physiologically relevant. Therefore, is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environ [...] | 0.873 |
| ABD29709.1 | thiE | SAOUHSC_00562 | SAOUHSC_02328 | Phosphomethylpyrimidine kinase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.992 |
| ABD29709.1 | thiM | SAOUHSC_00562 | SAOUHSC_02329 | Phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase, putative; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.933 |
| ABD31364.1 | ABD31559.1 | SAOUHSC_02330 | SAOUHSC_02545 | Phosphomethylpyrimidine kinase. | Conserved hypothetical protein. | 0.526 |
| ABD31364.1 | tenA | SAOUHSC_02330 | SAOUHSC_02331 | Phosphomethylpyrimidine kinase. | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity may not be physiologically relevant. Therefore, is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environ [...] | 0.998 |
| ABD31364.1 | thiE | SAOUHSC_02330 | SAOUHSC_02328 | Phosphomethylpyrimidine kinase. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
| ABD31364.1 | thiM | SAOUHSC_02330 | SAOUHSC_02329 | Phosphomethylpyrimidine kinase. | Hydroxyethylthiazole kinase, putative; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.996 |
| ABD31364.1 | yidC | SAOUHSC_02330 | SAOUHSC_02327 | Phosphomethylpyrimidine kinase. | Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.723 |
| ABD31559.1 | ABD29709.1 | SAOUHSC_02545 | SAOUHSC_00562 | Conserved hypothetical protein. | Phosphomethylpyrimidine kinase. | 0.526 |
| ABD31559.1 | ABD31364.1 | SAOUHSC_02545 | SAOUHSC_02330 | Conserved hypothetical protein. | Phosphomethylpyrimidine kinase. | 0.526 |
| ABD31559.1 | hisF | SAOUHSC_02545 | SAOUHSC_03008 | Conserved hypothetical protein. | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | 0.566 |
| ABD31559.1 | tenA | SAOUHSC_02545 | SAOUHSC_02331 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity may not be physiologically relevant. Therefore, is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environ [...] | 0.530 |
| ABD31559.1 | thiE | SAOUHSC_02545 | SAOUHSC_02328 | Conserved hypothetical protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.745 |
| ABD31559.1 | thiM | SAOUHSC_02545 | SAOUHSC_02329 | Conserved hypothetical protein. | Hydroxyethylthiazole kinase, putative; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.404 |
| ABD31559.1 | tilS | SAOUHSC_02545 | SAOUHSC_00484 | Conserved hypothetical protein. | Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. | 0.505 |
| ABD31949.1 | rsgA | SAOUHSC_02958 | SAOUHSC_01188 | Alkaline phosphatase III precursor, putative; Belongs to the alkaline phosphatase family. | Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.900 |
| ABD31949.1 | tenA | SAOUHSC_02958 | SAOUHSC_02331 | Alkaline phosphatase III precursor, putative; Belongs to the alkaline phosphatase family. | Conserved hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP). Is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity may not be physiologically relevant. Therefore, is probably involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the environ [...] | 0.900 |
| ABD31949.1 | thiE | SAOUHSC_02958 | SAOUHSC_02328 | Alkaline phosphatase III precursor, putative; Belongs to the alkaline phosphatase family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.900 |
| hisF | ABD31559.1 | SAOUHSC_03008 | SAOUHSC_02545 | Imidazole glycerol phosphate synthase subunit hisF, putative; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit; In the C-terminal section; belongs to the PRA-PH family. | Conserved hypothetical protein. | 0.566 |
