Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacDTagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family. (326 aa)    
Predicted Functional Partners:
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.997
ABD31470.1
Pts system, lactose-specific IIBC component, putative.
 
  
 0.978
lacB
Galactose-6-phosphate isomerase, LacB subunit.
 
  
 0.978
lacA
Galactose-6-phosphate isomerase, LacA subunit.
 
  
 0.966
ABD31471.1
PTS system lactose-specific IIA component, putative.
 
  
 0.945
lacG
6-phospho-beta-galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
  
 0.917
pfkA
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.906
lacR
Lactose phosphotransferase system repressor, putative; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer.
 
   
 0.817
ABD31624.1
Aldose 1-epimerase precursor, putative.
  
  
 0.631
codY
Conserved hypothetical protein; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
      
 0.468
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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