Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacBGalactose-6-phosphate isomerase, LacB subunit. (171 aa)    
Predicted Functional Partners:
lacA
Galactose-6-phosphate isomerase, LacA subunit.
 
  
 0.998
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.996
lacG
6-phospho-beta-galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.988
lacD
Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.978
ABD31470.1
Pts system, lactose-specific IIBC component, putative.
 
  
 0.964
glyA
Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
    0.921
ABD31471.1
PTS system lactose-specific IIA component, putative.
 
  
 0.919
pfkA
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.914
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
    0.868
lacR
Lactose phosphotransferase system repressor, putative; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer.
 
   
 0.792
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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