STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacBGalactose-6-phosphate isomerase, LacB subunit. (171 aa)    
Predicted Functional Partners:
lacD
Tagatose 1,6-diphosphate aldolase; Belongs to the aldolase LacD family.
 
  
 0.999
lacC
Tagatose-6-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
lacA
Galactose-6-phosphate isomerase, LacA subunit.
 
 
 0.999
lacG
6-phospho-beta-galactosidase; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.998
ABD31470.1
Pts system, lactose-specific IIBC component, putative.
 
  
 0.955
glyA
Serine hydroxymethyltransferase, putative; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
  0.933
ABD30296.1
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 0.918
pfkA
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.915
prs
Ribose-phosphate pyrophosphokinase, putative; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.902
ABD31471.1
PTS system lactose-specific IIA component, putative.
 
  
 0.900
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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