STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31535.1Conserved hypothetical protein. (295 aa)    
Predicted Functional Partners:
tcaA
Conserved hypothetical protein; Plays a major role in decreasing resistance to glycopeptide antibiotics; Belongs to the TcaA family.
  
     0.772
ABD30116.1
Transcriptional regulator, MarR family, putative.
  
     0.769
ABD31296.1
Conserved hypothetical protein.
  
     0.764
tagX
tagX protein, putative; Belongs to the glycosyltransferase 2 family.
  
     0.762
ABD30587.1
Conserved hypothetical protein.
  
     0.759
ABD31195.1
Conserved hypothetical protein.
  
     0.754
ABD32012.1
Conserved hypothetical protein.
  
     0.742
topB
DNA topoisomerase III, putative; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus remov [...]
       0.737
ABD29816.1
Conserved hypothetical protein.
  
     0.736
ABD31186.1
Conserved hypothetical protein.
  
     0.736
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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