Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ureBUrease, beta subunit, putative; Belongs to the urease beta subunit family. (136 aa)    
Predicted Functional Partners:
ureA
Urease, gamma subunit; Belongs to the urease gamma subunit family.
 0.999
ureC
Urease, alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 0.999
ureD
Urease accessory protein UreD, putative; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.998
ureF
Urease accessory protein UreF, putative; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.995
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.991
ureE
Urease accessory protein UreE, putative; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
   
 0.977
ABD31437.1
Arginase; Belongs to the arginase family.
    
  0.901
ABD31570.1
Urea transporter, putative.
 
   
 0.726
ABD29594.1
Glutamate synthase, large subunit, putative.
      
 0.520
ABD31308.1
Ammonium transporter.
  
  
 0.462
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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