Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ureEUrease accessory protein UreE, putative; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (150 aa)    
Predicted Functional Partners:
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.994
ureF
Urease accessory protein UreF, putative; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.993
ureD
Urease accessory protein UreD, putative; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.992
ureC
Urease, alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.985
ureB
Urease, beta subunit, putative; Belongs to the urease beta subunit family.
 
   
 0.977
ureA
Urease, gamma subunit; Belongs to the urease gamma subunit family.
 
  
 0.931
ABD31308.1
Ammonium transporter.
     
 0.711
ABD31570.1
Urea transporter, putative.
     
 0.711
ABD29594.1
Glutamate synthase, large subunit, putative.
     
 0.551
ABD29595.1
NADH-glutamate synthase small subunit, putative.
      
 0.520
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (20%) [HD]