Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABD31618.1Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family. (294 aa)    
Predicted Functional Partners:
ABD30038.1
Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family.
  
     0.758
hutI
Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
       0.705
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
       0.705
ABD29235.1
Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family.
  
     0.611
ABD29594.1
Glutamate synthase, large subunit, putative.
     
 0.506
ABD29468.1
Conserved hypothetical protein.
 
     0.487
rpoA
DNA-directed RNA polymerase alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.480
arcR
Conserved hypothetical protein; Positively regulates the expression of the arcABDCR operon under anaerobic conditions, by binding to the consensus motif 5'- TGTGAN(6)TCACA-3', thus playing an essential role in arginine catabolism. May also control the expression of genes encoding proteins which are involved in anaerobic metabolism. Can bind cyclic AMP.
   
 
 0.444
rpoB
RNA polymerase beta chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.438
ABD31615.1
Conserved hypothetical protein.
       0.438
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.