STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31687.1Respiratory nitrate reductase, delta subunit, putative. (196 aa)    
Predicted Functional Partners:
ABD31688.1
Nitrate reductase, beta subunit.
 
 
 0.999
ABD31689.1
Nitrate reductase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.999
ABD31686.1
Respiratory nitrate reductase, gamma subunit.
 
  
 0.998
ABD31685.1
Conserved hypothetical protein.
 
     0.930
narT
Conserved hypothetical protein; Probably required for nitrate uptake under anoxic conditions. Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity).
 
  
 0.925
nreB
Conserved hypothetical protein; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity).
 
     0.793
ABD31691.1
Assimilatory nitrite reductase [NAD(P)H], small subunit, putative.
  
  
 0.729
nreC
Conserved hypothetical protein; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
 
     0.646
ABD31692.1
Assimilatory nitrite reductase [NAD(P)H], large subunit, putative; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.578
ABD31690.1
uroporphyrin-III C-methyltransferase, putative; Belongs to the precorrin methyltransferase family.
  
    0.544
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.