Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABD31693.1Conserved hypothetical protein. (243 aa)    
Predicted Functional Partners:
ABD31690.1
uroporphyrin-III C-methyltransferase, putative; Belongs to the precorrin methyltransferase family.
 
  
 0.984
ABD31939.1
Siroheme synthase, putative.
 
  
 0.941
ABD31691.1
Assimilatory nitrite reductase [NAD(P)H], small subunit, putative.
  
  
 0.896
ABD31692.1
Assimilatory nitrite reductase [NAD(P)H], large subunit, putative; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.815
ABD31688.1
Nitrate reductase, beta subunit.
  
    0.673
ABD30100.1
Conserved hypothetical protein.
  
     0.518
ABD31687.1
Respiratory nitrate reductase, delta subunit, putative.
  
    0.489
ABD31686.1
Respiratory nitrate reductase, gamma subunit.
  
    0.488
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
      
 0.467
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.456
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
Server load: low (18%) [HD]