Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
flpConserved hypothetical protein; Its precise function is unknown. Has no penicillin-binding activity and is not involved in methicillin resistance. (498 aa)    
Predicted Functional Partners:
ABD31741.1
Conserved hypothetical protein.
       0.565
ABD29324.1
Conserved hypothetical protein; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.549
ABD29995.1
dltB protein, putative; Could be involved in the transport of activated D-alanine through the membrane.
 
  
 0.467
ABD29757.1
Conserved hypothetical protein.
  
     0.417
dltA
D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
 
  
 0.415
ABD31740.1
Membrane protein, putative.
       0.405
ABD32019.1
Conserved hypothetical protein; Belongs to the arylamine N-acetyltransferase family.
  
     0.403
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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