PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

Staphylococcal accessory regulator T, putative; Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha- hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression. Up- regulates sarS, which induces the expression of the cell wall- associated protein A (spa).

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

Conserved hypothetical protein; Positive regulator of RNAII and RNAIII in a cell density- dependent manner. It can contribute to the expression of virulence genes controlled by agr. May also regulate target genes via an agr- independent pathway.

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

Conserved hypothetical protein; Part of the pathway by which MgrA and SarA control autolysis. Involved in regulation of virulence and autolysis genes such as hla, splA, aur, scp, lrgB, scdA and atl. May also act as an activator for the expression of regulatory genes agr, lytSR and ArlRS.

Alpha-hemolysin precursor; Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity (By similarity). Belongs to the aerolysin family.

Staphylococcal accessory regulator T, putative; Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha- hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression. Up- regulates sarS, which induces the expression of the cell wall- associated protein A (spa).

Alpha-hemolysin precursor; Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity (By similarity). Belongs to the aerolysin family.

Conserved hypothetical protein; Promotes adhesion of bacterial cells to human squamous nasal epithelial cells, a phenomenon which is likely to be important in nasal colonization. Forms short, extremely dense and thin fibrils all over the bacterial surface. Does not bind to either buccal cells or non- differentiated keratinocytes. Promotes cellular aggregation leading to biofilm formation.

Peptidoglycan hydrolase, putative; Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan. Belongs to the peptidase M23B family.

Staphylococcal accessory regulator T, putative; Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha- hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression. Up- regulates sarS, which induces the expression of the cell wall- associated protein A (spa).

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

Staphylococcal accessory regulator T, putative; Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha- hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression. Up- regulates sarS, which induces the expression of the cell wall- associated protein A (spa).

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

Conserved hypothetical protein; Positive regulator of RNAII and RNAIII in a cell density- dependent manner. It can contribute to the expression of virulence genes controlled by agr. May also regulate target genes via an agr- independent pathway.

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

Conserved hypothetical protein; Part of the pathway by which MgrA and SarA control autolysis. Involved in regulation of virulence and autolysis genes such as hla, splA, aur, scp, lrgB, scdA and atl. May also act as an activator for the expression of regulatory genes agr, lytSR and ArlRS.

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

PTS system, glucose-specific component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

Staphylococcal accessory regulator T, putative; Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha- hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression. Up- regulates sarS, which induces the expression of the cell wall- associated protein A (spa).

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

Conserved hypothetical protein; Positive regulator of RNAII and RNAIII in a cell density- dependent manner. It can contribute to the expression of virulence genes controlled by agr. May also regulate target genes via an agr- independent pathway.

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

Conserved hypothetical protein; Part of the pathway by which MgrA and SarA control autolysis. Involved in regulation of virulence and autolysis genes such as hla, splA, aur, scp, lrgB, scdA and atl. May also act as an activator for the expression of regulatory genes agr, lytSR and ArlRS.

Conserved hypothetical protein; Negative regulator of sarA transcription at late exponential and stationary growth phases. It contributes to the modulation of target genes downstream of the sarA regulatory cascade. Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.

Conserved hypothetical protein; Involved in the regulation of virulence genes. Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb. Binds directly to the agr promoter region.

Staphylococcal accessory regulator T, putative; Transcriptional regulator acting as an intermediary between major regulators sarA and agr and virulence genes. Represses alpha- hemolysin (hla) gene expression. Down-regulates agr RNAIII expression by repressing sarU, a positive activator of agr expression. Up- regulates sarS, which induces the expression of the cell wall- associated protein A (spa).

PTS system glucose-specific IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in alpha- and beta-glucoside transport (By similarity).