node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABD29300.1 | ABD29308.1 | SAOUHSC_00119 | SAOUHSC_00127 | Capsular polysaccharide synthesis enzyme Cap8F. | cap5N protein/UDP-glucose 4-epimerase, putative. | 0.871 |
ABD29300.1 | ABD30622.1 | SAOUHSC_00119 | SAOUHSC_01541 | Capsular polysaccharide synthesis enzyme Cap8F. | Conserved hypothetical phage protein. | 0.993 |
ABD29300.1 | glmM | SAOUHSC_00119 | SAOUHSC_02405 | Capsular polysaccharide synthesis enzyme Cap8F. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | 0.604 |
ABD29300.1 | glmU | SAOUHSC_00119 | SAOUHSC_00471 | Capsular polysaccharide synthesis enzyme Cap8F. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.732 |
ABD29300.1 | gtaB | SAOUHSC_00119 | SAOUHSC_02801 | Capsular polysaccharide synthesis enzyme Cap8F. | UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP (Probable). This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). | 0.770 |
ABD29300.1 | icaA | SAOUHSC_00119 | SAOUHSC_03002 | Capsular polysaccharide synthesis enzyme Cap8F. | Intercellular adhesion protein A, putative; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity (By similarity). | 0.567 |
ABD29300.1 | pgcA | SAOUHSC_00119 | SAOUHSC_02793 | Capsular polysaccharide synthesis enzyme Cap8F. | Conserved hypothetical protein; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate (Probable). This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Belongs to the phosphohexose mutase family. | 0.604 |
ABD29300.1 | pgi | SAOUHSC_00119 | SAOUHSC_00900 | Capsular polysaccharide synthesis enzyme Cap8F. | Glucose-6-phosphate isomerase. | 0.412 |
ABD29308.1 | ABD29300.1 | SAOUHSC_00127 | SAOUHSC_00119 | cap5N protein/UDP-glucose 4-epimerase, putative. | Capsular polysaccharide synthesis enzyme Cap8F. | 0.871 |
ABD29308.1 | gtaB | SAOUHSC_00127 | SAOUHSC_02801 | cap5N protein/UDP-glucose 4-epimerase, putative. | UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP (Probable). This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). | 0.889 |
ABD30622.1 | ABD29300.1 | SAOUHSC_01541 | SAOUHSC_00119 | Conserved hypothetical phage protein. | Capsular polysaccharide synthesis enzyme Cap8F. | 0.993 |
ABD30622.1 | glmU | SAOUHSC_01541 | SAOUHSC_00471 | Conserved hypothetical phage protein. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.559 |
ABD30622.1 | gtaB | SAOUHSC_01541 | SAOUHSC_02801 | Conserved hypothetical phage protein. | UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP (Probable). This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). | 0.576 |
glmM | ABD29300.1 | SAOUHSC_02405 | SAOUHSC_00119 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | Capsular polysaccharide synthesis enzyme Cap8F. | 0.604 |
glmM | glmU | SAOUHSC_02405 | SAOUHSC_00471 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.991 |
glmM | gtaB | SAOUHSC_02405 | SAOUHSC_02801 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP (Probable). This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). | 0.578 |
glmM | pgcA | SAOUHSC_02405 | SAOUHSC_02793 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | Conserved hypothetical protein; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate (Probable). This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Belongs to the phosphohexose mutase family. | 0.405 |
glmM | pgi | SAOUHSC_02405 | SAOUHSC_00900 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. | Glucose-6-phosphate isomerase. | 0.578 |
glmU | ABD29300.1 | SAOUHSC_00471 | SAOUHSC_00119 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Capsular polysaccharide synthesis enzyme Cap8F. | 0.732 |
glmU | ABD30622.1 | SAOUHSC_00471 | SAOUHSC_01541 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Conserved hypothetical phage protein. | 0.559 |