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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31852.1Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family. (275 aa)    
Predicted Functional Partners:
ABD29593.1
Transcriptional regulator, lysR family, putative; Belongs to the LysR transcriptional regulatory family.
  
     0.766
ABD29233.1
Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family.
  
     0.747
ABD30038.1
Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family.
  
     0.693
cidA
Conserved hypothetical protein; Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypoth [...]
 
     0.662
cidB
Conserved hypothetical protein; Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypoth [...]
 
     0.623
ABD29235.1
Conserved hypothetical protein; Belongs to the LysR transcriptional regulatory family.
  
     0.561
ABD29594.1
Glutamate synthase, large subunit, putative.
  
  
 0.497
ABD31853.1
Conserved hypothetical protein; Belongs to the UPF0346 family.
       0.495
ABD31849.1
Pyruvate oxidase, putative; Belongs to the TPP enzyme family.
       0.409
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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