STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABD31873.1D-lactate dehydrogenase, putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.913
ABD31874.1
Conserved hypothetical protein.
 
  
  0.794
ABD31321.1
Conserved hypothetical protein.
    
  0.668
ldh1
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate (Potential). Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity).
   
 0.664
ldh2
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate (Potential). Contributes to S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells, despite playing a secondary role in this resistance mechanism (By similarity).
   
 0.664
ABD29225.1
Conserved hypothetical protein.
  
 
  0.644
ABD30367.1
Conserved hypothetical protein.
    
  0.637
ABD30901.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 
0.636
ABD30720.1
Conserved hypothetical protein.
   
 
  0.634
pflB
Formate acetyltransferase; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
     
 0.632
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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