Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABD31894.1Conserved hypothetical protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (234 aa)    
Predicted Functional Partners:
ABD31893.1
Conserved hypothetical protein.
 
     0.855
ABD29324.1
Conserved hypothetical protein; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.825
ABD31891.1
Conserved hypothetical protein.
 
 
   0.741
ABD31896.1
Conserved hypothetical protein; Belongs to the AB hydrolase superfamily.
 
  0.699
ABD29374.1
Conserved hypothetical protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.664
ABD31776.1
Conserved hypothetical protein.
  
     0.662
ABD31895.1
Conserved hypothetical protein.
 
    0.648
ABD31892.1
Conserved hypothetical protein.
 
     0.602
sbcD
Conserved hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity). Is probably part of the SOS regulon and involved in DNA recombination and repair.
  
 
   0.496
ABD31890.1
Conserved hypothetical protein.
       0.480
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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