STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
isaBConserved hypothetical protein; Belongs to the IsaB family. (175 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter ATP-binding protein, putative; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
 
 0.762
ABD30481.1
Phosphate ABC transporter, permease protein, putative.
  
 
 0.761
ABD30482.1
Conserved hypothetical protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
  
 
 0.761
ebh
Conserved hypothetical protein; Promotes bacterial attachment to both soluble and immobilized forms of fibronectin (Fn), in a dose-dependent and saturable manner.
   
  
 0.498
ebpS
Elastin binding protein; Promotes binding of soluble elastin peptides and tropoelastin to S.aureus cells although it is not able to promote bacterial adherence to immobilized elastin and, therefore, is not a microbial surface component recognizing adhesive matrix molecule (MSCRAMM). May be involved in sensing the environment or in nutrient transport, since its loss caused a growth defect.
   
 
 0.492
ABD30479.1
PhoU family, putative; Plays a role in the regulation of phosphate uptake.
  
  
 0.476
ABD31962.1
Conserved hypothetical protein.
       0.467
guaA
GMP synthase, putative; Catalyzes the synthesis of GMP from XMP.
     
 0.451
ribBA
Riboflavin biosynthesis protein, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
   0.451
isaA
Immunodominant antigen A, putative; Is able to cleave peptidoglycan. Belongs to the transglycosylase family. IsaA subfamily.
      
 0.450
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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