Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ABD32029.1Helix-turn-helix domain protein. (189 aa)    
Predicted Functional Partners:
ABD31667.1
Conserved hypothetical protein.
  
     0.548
ABD31909.1
Conserved hypothetical protein.
  
     0.513
ABD31887.1
Conserved hypothetical protein.
  
     0.458
ABD29801.1
ABC transporter permease, putative.
  
     0.451
ABD32022.1
Permease, putative.
  
     0.444
srtB
Conserved hypothetical protein; Transpeptidase that anchors surface proteins to the cell wall (Probable). Recognizes and modifies its substrate by proteolytic cleavage of a C- terminal sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall (Probable). This sortase recognizes an Asn-Pro-Gln- Thr-Asn (NPQTN) motif in IsdC, which is cleaved by the sortase between the threonine and aspargine residues; may only have 1 substrate in this bacterium (Pro [...]
  
     0.443
ABD32030.1
Conserved hypothetical protein.
       0.419
Your Current Organism:
Staphylococcus aureus
NCBI taxonomy Id: 93061
Other names: S. aureus subsp. aureus NCTC 8325, Staphylococcus aureus NCTC 8325, Staphylococcus aureus subsp. aureus NCTC 8325, Staphylococcus aureus subsp. aureus str. NCTC 8325, Staphylococcus aureus subsp. aureus strain NCTC 8325
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