STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggDNA-(apurinic or apyrimidinic site) lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (207 aa)    
Predicted Functional Partners:
SiRe_1181
Conserved hypothetical protein.
       0.803
SiRe_1176
DNA topoisomerase I.
 
     0.597
SiRe_1182
Conserved hypothetical protein.
       0.582
SiRe_1183
Conserved hypothetical protein.
       0.563
SiRe_1178
Serine-pyruvate transaminase.
 
     0.553
SiRe_1179
D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein.
       0.487
rpoK
RNA polymerase Rpb6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
       0.474
rad50
Recombination repair enzyme Rad50 like protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
  
   
 0.443
SiRe_2547
Rieske (2Fe-2S) domain protein.
 
     0.408
Your Current Organism:
Sulfolobus islandicus
NCBI taxonomy Id: 930945
Other names: S. islandicus REY15A, Sulfolobus islandicus REY15A, Sulfolobus islandicus str. REY15A, Sulfolobus islandicus strain REY15A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.