A0A0D0CY17 protein (Paxillus rubicundulus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

A0A0D0CY17

Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence. (313 aa)

Predicted Functional Partners:

A0A0D0DJ05

0.992

A0A0D0DX85

0.992

A0A0D0E5M2

0.992

A0A0D0EB92

0.992

A0A0D0ECF5

0.992

A0A0D0DW23

0.991

A0A0D0CEC1

0.988

A0A0D0DXS2

0.915

A0A0D0DV22

0.907

A0A0D0DUA5

0.874

Your Current Organism:

Paxillus rubicundulus

NCBI taxonomy Id: 930991
Other names: P. rubicundulus Ve08.2h10, Paxillus rubicundulus Ve08.2h10

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A0D0CEC1	A0A0D0CY17	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	0.988
A0A0D0CEC1	A0A0D0DJ05	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_74, whole genome shotgun sequence.	0.999
A0A0D0CEC1	A0A0D0DUA5	T-complex protein 1 subunit gamma.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.862
A0A0D0CEC1	A0A0D0DV22	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_383, whole genome shotgun sequence; Belongs to the GroES chaperonin family.	0.907
A0A0D0CEC1	A0A0D0DW23	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_322, whole genome shotgun sequence.	0.999
A0A0D0CEC1	A0A0D0DX85	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_19, whole genome shotgun sequence.	0.999
A0A0D0CEC1	A0A0D0DXS2	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_12, whole genome shotgun sequence.	0.915
A0A0D0CEC1	A0A0D0E5M2	T-complex protein 1 subunit gamma.	Unplaced genomic scaffold scaffold_23, whole genome shotgun sequence.	0.999
A0A0D0CEC1	A0A0D0EB92	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
A0A0D0CEC1	A0A0D0ECF5	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit delta.	0.999
A0A0D0CY17	A0A0D0CEC1	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	T-complex protein 1 subunit gamma.	0.988
A0A0D0CY17	A0A0D0DJ05	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Unplaced genomic scaffold scaffold_74, whole genome shotgun sequence.	0.992
A0A0D0CY17	A0A0D0DUA5	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.874
A0A0D0CY17	A0A0D0DV22	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Unplaced genomic scaffold scaffold_383, whole genome shotgun sequence; Belongs to the GroES chaperonin family.	0.907
A0A0D0CY17	A0A0D0DW23	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Unplaced genomic scaffold scaffold_322, whole genome shotgun sequence.	0.991
A0A0D0CY17	A0A0D0DX85	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Unplaced genomic scaffold scaffold_19, whole genome shotgun sequence.	0.992
A0A0D0CY17	A0A0D0DXS2	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Unplaced genomic scaffold scaffold_12, whole genome shotgun sequence.	0.915
A0A0D0CY17	A0A0D0E5M2	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	Unplaced genomic scaffold scaffold_23, whole genome shotgun sequence.	0.992
A0A0D0CY17	A0A0D0EB92	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.992
A0A0D0CY17	A0A0D0ECF5	Unplaced genomic scaffold scaffold_1194, whole genome shotgun sequence.	T-complex protein 1 subunit delta.	0.992

page 1 of 6

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000724

Double-strand break repair via homologous recombination

3 of 4

2.43

1.93

0.00054

GO:0006281

DNA repair

4 of 50

1.46

1.23

0.0020

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003690

Double-stranded DNA binding

3 of 14

1.89

1.25

0.0057

GO:0003678

DNA helicase activity

3 of 14

1.89

1.25

0.0057

GO:0004527

Exonuclease activity

3 of 20

1.73

1.2

0.0057

GO:0016887

ATP hydrolysis activity

3 of 41

1.42

0.86

0.0179

GO:0008408

3-5 exonuclease activity

2 of 9

1.9

0.86

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033202

DNA helicase complex

3 of 8

2.13

2.0

0.00027

GO:1902494

Catalytic complex

4 of 68

1.33

1.21

0.00092

GO:0032991

Protein-containing complex

5 of 170

1.03

0.88

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1230

PD-(D/E)XK nuclease superfamily, and CBS domain

4 of 6

2.38

3.11

3.40e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033202

DNA helicase complex

3 of 13

1.92

1.48

0.0020

GOCC:0044815

DNA packaging complex

3 of 15

1.86

1.46

0.0020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0269

Exonuclease

3 of 11

1.99

1.9

0.00033

KW-0234

DNA repair

4 of 31

1.67

1.72

0.00024

KW-0227

DNA damage

4 of 31

1.67

1.72

0.00024

KW-0347

Helicase

3 of 20

1.73

1.5

0.0012

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13361

UvrD-like helicase C-terminal domain

3 of 3

2.56

2.31

0.00013

PF12705

PD-(D/E)XK nuclease superfamily

3 of 4

2.43

2.28

0.00013

PF13245

AAA domain

2 of 5

2.16

0.99

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038726

PD-(D/E)XK endonuclease-like domain, AddAB-type

3 of 4

2.43

1.92

0.00058

IPR011604

PD-(D/E)XK endonuclease-like domain superfamily

3 of 4

2.43

1.92

0.00058

IPR011335

Restriction endonuclease type II-like

3 of 7

2.19

1.82

0.00067

IPR014016

UvrD-like helicase, ATP-binding domain

3 of 8

2.13

1.8

0.00068

IPR000212

DNA helicase, UvrD/REP type

3 of 8

2.13

1.8

0.00068

(more ...)

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