STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0D0DD85Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1559 aa)    
Predicted Functional Partners:
A0A0D0E5U1
Unplaced genomic scaffold scaffold_18, whole genome shotgun sequence.
    
 0.996
A0A0D0DYC8
Unplaced genomic scaffold scaffold_5, whole genome shotgun sequence.
   
 0.994
A0A0D0DTQ0
Unplaced genomic scaffold scaffold_502, whole genome shotgun sequence.
   
 0.986
A0A0D0DW86
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
 0.985
A0A0D0E7K7
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
     
 0.982
A0A0D0DG35
Unplaced genomic scaffold scaffold_146, whole genome shotgun sequence.
   
 0.977
A0A0D0E0E4
Unplaced genomic scaffold scaffold_146, whole genome shotgun sequence.
   
 0.977
A0A0D0E2A9
Unplaced genomic scaffold scaffold_631, whole genome shotgun sequence.
   
 0.971
A0A0D0EBT2
Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.967
A0A0D0E6M2
Unplaced genomic scaffold scaffold_6, whole genome shotgun sequence.
    
 0.964
Your Current Organism:
Paxillus rubicundulus
NCBI taxonomy Id: 930991
Other names: P. rubicundulus Ve08.2h10, Paxillus rubicundulus Ve08.2h10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.