STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0D0DZ36DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (730 aa)    
Predicted Functional Partners:
A0A0D0CCB4
Unplaced genomic scaffold scaffold_1199, whole genome shotgun sequence.
    
 0.996
A0A0D0E3B2
Unplaced genomic scaffold scaffold_565, whole genome shotgun sequence.
    
 0.970
A0A0D0DID2
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 0.969
A0A0D0E288
Unplaced genomic scaffold scaffold_85, whole genome shotgun sequence.
   
 0.967
A0A0D0DZX2
Unplaced genomic scaffold scaffold_170, whole genome shotgun sequence.
    
 0.961
A0A0D0DWT0
Unplaced genomic scaffold scaffold_25, whole genome shotgun sequence.
   
 0.957
A0A0D0D4I7
Unplaced genomic scaffold scaffold_1742, whole genome shotgun sequence.
  
 0.946
A0A0D0BQC1
Unplaced genomic scaffold scaffold_4645, whole genome shotgun sequence.
   
 0.942
A0A0D0BZU6
Unplaced genomic scaffold scaffold_2575, whole genome shotgun sequence.
   
 0.942
A0A0D0DCA3
Unplaced genomic scaffold scaffold_1815, whole genome shotgun sequence.
   
 0.942
Your Current Organism:
Paxillus rubicundulus
NCBI taxonomy Id: 930991
Other names: P. rubicundulus Ve08.2h10, Paxillus rubicundulus Ve08.2h10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.