STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (322 aa)    
Predicted Functional Partners:
TAH18
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    
 0.983
A0A0D0DF69
Unplaced genomic scaffold scaffold_172, whole genome shotgun sequence.
    
 
 0.945
A0A0D0DH54
Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
    
 
 0.930
A0A0D0C6M2
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450.
    
 0.922
A0A0D0DN39
Unplaced genomic scaffold scaffold_15, whole genome shotgun sequence.
    
 0.922
A0A0D0EBP9
Unplaced genomic scaffold scaffold_89, whole genome shotgun sequence.
    
 0.922
A0A0D0DVR3
Unplaced genomic scaffold scaffold_49, whole genome shotgun sequence; Belongs to the BolA/IbaG family.
    
 
 0.868
A0A0D0EBL8
Unplaced genomic scaffold scaffold_96, whole genome shotgun sequence; Belongs to the BolA/IbaG family.
    
 
 0.848
A0A0D0ECN8
Unplaced genomic scaffold scaffold_30, whole genome shotgun sequence; Belongs to the BolA/IbaG family.
    
 
 0.830
CFD1
Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
   
 0.820
Your Current Organism:
Paxillus rubicundulus
NCBI taxonomy Id: 930991
Other names: P. rubicundulus Ve08.2h10, Paxillus rubicundulus Ve08.2h10
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