STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (406 aa)    
Predicted Functional Partners:
A0A0D0D8V6
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.999
A0A0D0DNZ3
DNA polymerase.
   
 0.990
A0A0D0DT61
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.979
A0A0D0DW10
Unplaced genomic scaffold scaffold_324, whole genome shotgun sequence.
   
 0.972
A0A0D0D4I9
Unplaced genomic scaffold scaffold_3663, whole genome shotgun sequence.
   
 0.969
A0A0D0DPS8
DNA ligase.
   
 0.969
A0A0D0ECB1
DNA ligase.
   
 0.969
A0A0D0DVD4
Unplaced genomic scaffold scaffold_364, whole genome shotgun sequence.
   
 0.954
A0A0D0DJ33
Unplaced genomic scaffold scaffold_610, whole genome shotgun sequence.
   
 0.951
A0A0D0CYX8
Replication factor C subunit 1.
   
 0.948
Your Current Organism:
Paxillus rubicundulus
NCBI taxonomy Id: 930991
Other names: P. rubicundulus Ve08.2h10, Paxillus rubicundulus Ve08.2h10
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.