| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALC04930.1 | ALC06184.1 | CDES_02350 | CDES_08960 | uroporphyrinogen-III synthase. | Hypothetical protein; Belongs to the precorrin methyltransferase family. | 0.939 |
| ALC04930.1 | cobT | CDES_02350 | CDES_09980 | uroporphyrinogen-III synthase. | Nicotinate-nucleotide- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.728 |
| ALC04930.1 | cysH | CDES_02350 | CDES_12610 | uroporphyrinogen-III synthase. | Phosphoadenosine-phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.625 |
| ALC04930.1 | hemA | CDES_02350 | CDES_02290 | uroporphyrinogen-III synthase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.970 |
| ALC04930.1 | hemB | CDES_02350 | CDES_02360 | uroporphyrinogen-III synthase. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.996 |
| ALC04930.1 | hemC | CDES_02350 | CDES_02295 | uroporphyrinogen-III synthase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| ALC04930.1 | hemE | CDES_02350 | CDES_02380 | uroporphyrinogen-III synthase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.963 |
| ALC04930.1 | hemL | CDES_02350 | CDES_02390 | uroporphyrinogen-III synthase. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.858 |
| ALC04930.1 | sir2 | CDES_02350 | CDES_12615 | uroporphyrinogen-III synthase. | Sulfite reductase [ferredoxin] 2; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.721 |
| ALC06184.1 | ALC04930.1 | CDES_08960 | CDES_02350 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase. | 0.939 |
| ALC06184.1 | cobT | CDES_08960 | CDES_09980 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Nicotinate-nucleotide- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.736 |
| ALC06184.1 | cysH | CDES_08960 | CDES_12610 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Phosphoadenosine-phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.719 |
| ALC06184.1 | hemA | CDES_08960 | CDES_02290 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.762 |
| ALC06184.1 | hemB | CDES_08960 | CDES_02360 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.855 |
| ALC06184.1 | hemC | CDES_08960 | CDES_02295 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.988 |
| ALC06184.1 | hemE | CDES_08960 | CDES_02380 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.913 |
| ALC06184.1 | hemL | CDES_08960 | CDES_02390 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.647 |
| ALC06184.1 | selO | CDES_08960 | CDES_08965 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | UPF0061-like protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. | 0.682 |
| ALC06184.1 | sir2 | CDES_08960 | CDES_12615 | Hypothetical protein; Belongs to the precorrin methyltransferase family. | Sulfite reductase [ferredoxin] 2; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.839 |
| cobT | ALC04930.1 | CDES_09980 | CDES_02350 | Nicotinate-nucleotide- dimethylbenzimidazolephosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | uroporphyrinogen-III synthase. | 0.728 |