STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C448_00170COG0286 Type I restriction-modification system methyltransferase subunit. (239 aa)    
Predicted Functional Partners:
C448_00165
Restriction modification system DNA specificity subunit; COG0732 Restriction endonuclease S subunits.
 
 0.996
C448_00175
N-6 DNA methylase; COG0286 Type I restriction-modification system methyltransferase subunit.
     0.992
C448_01504
COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.930
C448_01509
Restriction endonuclease, type I, EcoRI, R subunit/Type III.
 
 
 0.923
C448_00160
Hypothetical protein; COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.
 
 
 0.904
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.485
C448_00180
Coenzyme A transferase; COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase.
       0.413
Your Current Organism:
Halococcus morrhuae
NCBI taxonomy Id: 931277
Other names: H. morrhuae DSM 1307, Halococcus morrhuae DSM 1307, Halococcus morrhuae JCM 8876, Halococcus morrhuae NRC 16008
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