STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C448_03496COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit. (367 aa)    
Predicted Functional Partners:
C448_03486
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
 0.999
C448_03491
Transketolase central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
 0.999
C448_08124
Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
 0.999
C448_03481
COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
 
 0.972
C448_00742
COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
 
 
 0.902
C448_12786
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.807
C448_08414
CoA-binding domain protein; COG1042 Acyl-CoA synthetase (NDP forming).
    
  0.784
C448_00285
Pyridine nucleotide-disulfide oxidoreductase dimerization region; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.776
C448_12801
COG0281 Malic enzyme.
   
 
 0.725
C448_15199
COG0281 Malic enzyme.
   
 
 0.725
Your Current Organism:
Halococcus morrhuae
NCBI taxonomy Id: 931277
Other names: H. morrhuae DSM 1307, Halococcus morrhuae DSM 1307, Halococcus morrhuae JCM 8876, Halococcus morrhuae NRC 16008
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.