STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C448_15269Dimethylglycine dehydrogenase; COG0665 Glycine/D-amino acid oxidases (deaminating). (834 aa)    
Predicted Functional Partners:
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.946
C448_14774
Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain.
 
 0.913
C448_14769
Glycine dehydrogenase subunit 1; COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain.
 
 0.902
C448_05888
FAD dependent oxidoreductase; COG0665 Glycine/D-amino acid oxidases (deaminating).
 
 0.869
C448_15264
COG1171 Threonine dehydratase.
  
 
 0.835
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.800
C448_15289
COG0685 5,10-methylenetetrahydrofolate reductase.
 
 
 0.787
C448_10502
Formimidoyltetrahydrofolate cyclodeaminase; COG3404 Methenyl tetrahydrofolate cyclohydrolase.
  
 
 0.770
C448_05191
Phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN.
   
 
 0.665
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 0.642
Your Current Organism:
Halococcus morrhuae
NCBI taxonomy Id: 931277
Other names: H. morrhuae DSM 1307, Halococcus morrhuae DSM 1307, Halococcus morrhuae JCM 8876, Halococcus morrhuae NRC 16008
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