AGO2 protein (Notamacropus eugenii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AGO2

Argonaute RISC catalytic component 2. (853 aa)

Predicted Functional Partners:

ENSMEUP00000000576

0.987

TARBP2

0.964

TNRC6B

0.938

DROSHA

0.928

PRKRA

0.896

AGO3

0.884

AGO1

0.884

AGO4

0.883

DDX6

0.867

ENSMEUP00000001366

0.851

Your Current Organism:

Notamacropus eugenii

NCBI taxonomy Id: 9315
Other names: Macropus eugenii, N. eugenii, tammar wallaby

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSMEUP00000012250	ENSMEUP00000001279	Argonaute RISC component 1.	Argonaute RISC catalytic component 2.	0.884
AGO1	DDX6	ENSMEUP00000012250	ENSMEUP00000009627	Argonaute RISC component 1.	DEAD-box helicase 6.	0.704
AGO1	DROSHA	ENSMEUP00000012250	ENSMEUP00000001884	Argonaute RISC component 1.	Drosha ribonuclease III.	0.889
AGO1	ENSMEUP00000000576	ENSMEUP00000012250	ENSMEUP00000000576	Argonaute RISC component 1.	annotation not available	0.937
AGO1	ENSMEUP00000001366	ENSMEUP00000012250	ENSMEUP00000001366	Argonaute RISC component 1.	annotation not available	0.583
AGO1	PRKRA	ENSMEUP00000012250	ENSMEUP00000002398	Argonaute RISC component 1.	Protein activator of interferon induced protein kinase EIF2AK2.	0.849
AGO1	TARBP2	ENSMEUP00000012250	ENSMEUP00000001752	Argonaute RISC component 1.	TARBP2 subunit of RISC loading complex.	0.849
AGO1	TNRC6B	ENSMEUP00000012250	ENSMEUP00000013184	Argonaute RISC component 1.	Trinucleotide repeat containing adaptor 6B.	0.741
AGO2	AGO1	ENSMEUP00000001279	ENSMEUP00000012250	Argonaute RISC catalytic component 2.	Argonaute RISC component 1.	0.884
AGO2	AGO3	ENSMEUP00000001279	ENSMEUP00000008410	Argonaute RISC catalytic component 2.	Argonaute RISC catalytic component 3.	0.884
AGO2	AGO4	ENSMEUP00000001279	ENSMEUP00000000949	Argonaute RISC catalytic component 2.	Argonaute RISC component 4.	0.883
AGO2	DDX6	ENSMEUP00000001279	ENSMEUP00000009627	Argonaute RISC catalytic component 2.	DEAD-box helicase 6.	0.867
AGO2	DROSHA	ENSMEUP00000001279	ENSMEUP00000001884	Argonaute RISC catalytic component 2.	Drosha ribonuclease III.	0.928
AGO2	ENSMEUP00000000576	ENSMEUP00000001279	ENSMEUP00000000576	Argonaute RISC catalytic component 2.	annotation not available	0.987
AGO2	ENSMEUP00000001366	ENSMEUP00000001279	ENSMEUP00000001366	Argonaute RISC catalytic component 2.	annotation not available	0.851
AGO2	PRKRA	ENSMEUP00000001279	ENSMEUP00000002398	Argonaute RISC catalytic component 2.	Protein activator of interferon induced protein kinase EIF2AK2.	0.896
AGO2	TARBP2	ENSMEUP00000001279	ENSMEUP00000001752	Argonaute RISC catalytic component 2.	TARBP2 subunit of RISC loading complex.	0.964
AGO2	TNRC6B	ENSMEUP00000001279	ENSMEUP00000013184	Argonaute RISC catalytic component 2.	Trinucleotide repeat containing adaptor 6B.	0.938
AGO3	AGO2	ENSMEUP00000008410	ENSMEUP00000001279	Argonaute RISC catalytic component 3.	Argonaute RISC catalytic component 2.	0.884
AGO3	DDX6	ENSMEUP00000008410	ENSMEUP00000009627	Argonaute RISC catalytic component 3.	DEAD-box helicase 6.	0.704