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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BORABORA aurora kinase A activator. (614 aa)    
Predicted Functional Partners:
PLK1
Polo like kinase 1.
   
 0.978
ENSMEUP00000014312
annotation not available
   
 0.883
ENSMEUP00000001129
annotation not available
   
 0.873
PLK3
Polo like kinase 3.
   
 0.873
PLK2
Polo like kinase 2.
   
 0.873
AURKB
Aurora kinase B.
   
 0.853
PLK4
Polo like kinase 4.
   
 0.835
CDK1
Cyclin dependent kinase 1.
   
 
 0.807
ENSMEUP00000011376
annotation not available
   
 
 0.780
ENSMEUP00000011705
annotation not available
   
 
  0.770
Your Current Organism:
Notamacropus eugenii
NCBI taxonomy Id: 9315
Other names: Macropus eugenii, N. eugenii, tammar wallaby
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.