STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHB59036.1KEGG: rop:ROP_45840 putative 4-hydroxybutyrate CoA-transferase. (408 aa)    
Predicted Functional Partners:
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.947
EHB59035.1
KEGG: rop:ROP_45850 hydroxymethylglutaryl-CoA lyase; PFAM: Pyruvate carboxyltransferase.
    
 0.939
EHB58100.1
TIGRFAM: Citrate synthase, type II; KEGG: msm:MSMEG_5672 type II citrate synthase; PFAM: Citrate synthase-like; Belongs to the citrate synthase family.
  
 0.937
EHB50584.1
TIGRFAM: Methylmalonyl-CoA mutase, beta chain; KEGG: mkm:Mkms_3184 methylmalonyl-CoA mutase, beta subunit; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic.
  
 
 0.933
EHB50585.1
TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; Methylmalonyl-CoA mutase, C-terminal; KEGG: msm:MSMEG_3159 methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; Cobalamin (vitamin B12)-binding.
  
 
 0.933
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.929
EHB55818.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.896
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 0.885
EHB59037.1
acetyl-CoA acetyltransferase; TIGRFAM: Thiolase; KEGG: rop:ROP_45830 putative acetyl-CoA acyltransferase; PFAM: Thiolase, C-terminal; Thiolase, N-terminal; Belongs to the thiolase-like superfamily. Thiolase family.
    
 0.882
EHB59039.1
KEGG: rop:ROP_45810 acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central domain.
 
 
 0.867
Your Current Organism:
Mycolicibacterium rhodesiae JS60
NCBI taxonomy Id: 931627
Other names: M. rhodesiae JS60, Mycobacterium rhodesiae JS60
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