Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iscRRrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)    
Predicted Functional Partners:
iscU
Scaffolding protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
  
 0.981
iscS_2
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.960
iscA
Forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
 
  
 0.946
hscB
Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
  
 0.926
iscS_3
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
  
 0.886
iscS_1
Class V aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.853
fdx_2
2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.660
nsrR
Rrf2 family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.543
AKH73501.1
Recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.510
yfkJ
Phosphotyrosine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
    0.485
Your Current Organism:
Pandoraea apista
NCBI taxonomy Id: 93218
Other names: ATCC BAA-61, CCUG 38412, CIP 106627, DSM 16535, LMG 16407, LMG:16407, NCTC 13158, P. apista, Pandoraea apista Coenye et al. 2000
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