STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (499 aa)    
Predicted Functional Partners:
ALS59792.1
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.925
ALS60917.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
 
 
 0.924
ALS59793.1
Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.921
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.916
ALS59219.1
Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.901
surE
5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.901
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
ppnP
Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
ALS60486.1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.900
ALS63254.1
Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
  0.900
Your Current Organism:
Pandoraea norimbergensis
NCBI taxonomy Id: 93219
Other names: ATCC BAA-65, Burkholderia norimbergensis, CCUG 39188, CFBP 4792, CIP 105463, DSM 11628, JCM 10565, LMG 18379, LMG:18379, NCTC 13162, P. norimbergensis, strain R2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.