STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
srrBTwo-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)    
Predicted Functional Partners:
phoP
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.973
rpfC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.816
kdpC
Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.815
pleD_1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.803
rstA_1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.731
copR
Response regulator in two-component regulatory system with CusS; regulates the copper efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.715
baeR
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.713
ompR
Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.706
basR_1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.696
cheY_2
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.694
Your Current Organism:
Pandoraea pulmonicola
NCBI taxonomy Id: 93221
Other names: ATCC BAA-62, ATCC:BAA:62, CCUG 38759, CIP 106625, DSM 16583, LMG 18106, LMG:18106, NCTC 13159, P. pulmonicola, Pandoraea pulmonicola Coenye et al. 2000
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