Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJC19815.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (284 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.903
dmdA_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.832
dmdA_2
3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.817
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.688
AJC20316.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.517
pabB
Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.514
lgrD_1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.508
tktA
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family.
 
  
 0.489
katA
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family.
   
 0.466
gltB_2
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.451
Your Current Organism:
Pandoraea pulmonicola
NCBI taxonomy Id: 93221
Other names: ATCC BAA-62, ATCC:BAA:62, CCUG 38759, CIP 106625, DSM 16583, LMG 18106, LMG:18106, NCTC 13159, P. pulmonicola, Pandoraea pulmonicola Coenye et al. 2000
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.