STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hmrR_1MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)    
Predicted Functional Partners:
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.720
nudF
ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.690
AJC19854.1
Adenylyl-sulfate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.675
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.656
zntR_2
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.614
rpfC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.554
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.544
glnA_1
Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.540
dhmA
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.538
cueR_3
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.508
Your Current Organism:
Pandoraea pulmonicola
NCBI taxonomy Id: 93221
Other names: ATCC BAA-62, ATCC:BAA:62, CCUG 38759, CIP 106625, DSM 16583, LMG 18106, LMG:18106, NCTC 13159, P. pulmonicola, Pandoraea pulmonicola Coenye et al. 2000
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