| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroE | pabB | RO07_05335 | RO07_03495 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.697 |
| aroE | pheA | RO07_05335 | RO07_15070 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
| aroE | trpA | RO07_05335 | RO07_18265 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.627 |
| aroE | trpB | RO07_05335 | RO07_18255 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.605 |
| aroE | trpC | RO07_05335 | RO07_05790 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Indole-3-glycerol-phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.845 |
| aroE | trpD2_2 | RO07_05335 | RO07_05785 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.488 |
| aroE | trpE | RO07_05335 | RO07_05775 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.626 |
| aroE | trpF | RO07_05335 | RO07_18250 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | N-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. | 0.472 |
| aroE | trpG | RO07_05335 | RO07_05780 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Aminodeoxychorismate/anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.887 |
| pabB | aroE | RO07_03495 | RO07_05335 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.697 |
| pabB | pheA | RO07_03495 | RO07_15070 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| pabB | trpA | RO07_03495 | RO07_18265 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.961 |
| pabB | trpB | RO07_03495 | RO07_18255 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.959 |
| pabB | trpC | RO07_03495 | RO07_05790 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Indole-3-glycerol-phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.988 |
| pabB | trpD2_1 | RO07_03495 | RO07_11095 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-binding protein YbiB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.971 |
| pabB | trpD2_2 | RO07_03495 | RO07_05785 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.987 |
| pabB | trpE | RO07_03495 | RO07_05775 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.888 |
| pabB | trpF | RO07_03495 | RO07_18250 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. | 0.951 |
| pabB | trpG | RO07_03495 | RO07_05780 | Aminodeoxychorismate synthase component I; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminodeoxychorismate/anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| pheA | aroE | RO07_15070 | RO07_05335 | Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.823 |