| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC22197.1 | adhB_1 | RO07_19970 | RO07_06305 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-threonine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| AJC22197.1 | aldB | RO07_19970 | RO07_06300 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| AJC22197.1 | dmpF | RO07_19970 | RO07_16235 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.900 |
| AJC22197.1 | flhA_4 | RO07_19970 | RO07_04520 | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.915 |
| acs | acsA_1 | RO07_16390 | RO07_13145 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.922 |
| acs | acsA_3 | RO07_16390 | RO07_23865 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.915 |
| acs | aldB | RO07_16390 | RO07_06300 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| acs | bclA_3 | RO07_16390 | RO07_23175 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| acs | dmpF | RO07_16390 | RO07_16235 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.910 |
| acs | poxB_1 | RO07_16390 | RO07_22645 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.901 |
| acs | poxB_2 | RO07_16390 | RO07_21295 | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.901 |
| acsA_1 | acs | RO07_13145 | RO07_16390 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
| acsA_1 | acsA_3 | RO07_13145 | RO07_23865 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| acsA_1 | aldB | RO07_13145 | RO07_06300 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. | 0.910 |
| acsA_1 | bclA_3 | RO07_13145 | RO07_23175 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.923 |
| acsA_1 | dmpF | RO07_13145 | RO07_16235 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.910 |
| acsA_1 | poxB_1 | RO07_13145 | RO07_22645 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate dehydrogenase; Catalyzes the formation of acetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.901 |
| acsA_1 | poxB_2 | RO07_13145 | RO07_21295 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Thiamine pyrophosphate-requiring protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.901 |
| acsA_3 | acs | RO07_23865 | RO07_16390 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.915 |
| acsA_3 | acsA_1 | RO07_23865 | RO07_13145 | AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.920 |