| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| galE_1 | glmU | RO07_07450 | RO07_09950 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.913 |
| galE_1 | gtaB | RO07_07450 | RO07_24630 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.854 |
| galE_1 | lpxA | RO07_07450 | RO07_19870 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.819 |
| galE_1 | murA_1 | RO07_07450 | RO07_06540 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.903 |
| galE_1 | murA_2 | RO07_07450 | RO07_04435 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
| galE_1 | rmlA | RO07_07450 | RO07_05175 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.446 |
| galE_1 | wecB | RO07_07450 | RO07_06140 | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.928 |
| glmU | galE_1 | RO07_09950 | RO07_07450 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| glmU | gtaB | RO07_09950 | RO07_24630 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
| glmU | lpxA | RO07_09950 | RO07_19870 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.854 |
| glmU | murA_1 | RO07_09950 | RO07_06540 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.949 |
| glmU | murA_2 | RO07_09950 | RO07_04435 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.938 |
| glmU | murC | RO07_09950 | RO07_05600 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.531 |
| glmU | wecB | RO07_09950 | RO07_06140 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.945 |
| gtaB | galE_1 | RO07_24630 | RO07_07450 | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Vi polysaccharide biosynthesis protein VipB/TviC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.854 |
| gtaB | glmU | RO07_24630 | RO07_09950 | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.925 |
| gtaB | murA_1 | RO07_24630 | RO07_06540 | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.851 |
| gtaB | murA_2 | RO07_24630 | RO07_04435 | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.851 |
| gtaB | wecB | RO07_24630 | RO07_06140 | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.904 |
| hisG | murA_1 | RO07_06535 | RO07_06540 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.836 |
