| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dmdA_1 | dmdA_2 | RO07_17445 | RO07_00645 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| dmdA_1 | ilvC | RO07_17445 | RO07_23655 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.970 |
| dmdA_1 | ilvD_1 | RO07_17445 | RO07_14985 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.876 |
| dmdA_1 | ilvD_2 | RO07_17445 | RO07_14980 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.893 |
| dmdA_1 | ilvD_6 | RO07_17445 | RO07_01105 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.909 |
| dmdA_1 | ilvD_7 | RO07_17445 | RO07_24340 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.906 |
| dmdA_1 | ilvH | RO07_17445 | RO07_23660 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
| dmdA_1 | mdlC | RO07_17445 | RO07_09555 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Benzoylformate decarboxylase; Catalyzes the formation of benzaldehyde from benzoylformate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.803 |
| dmdA_2 | dmdA_1 | RO07_00645 | RO07_17445 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.998 |
| dmdA_2 | ilvC | RO07_00645 | RO07_23655 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.968 |
| dmdA_2 | ilvD_1 | RO07_00645 | RO07_14985 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.873 |
| dmdA_2 | ilvD_2 | RO07_00645 | RO07_14980 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.894 |
| dmdA_2 | ilvD_6 | RO07_00645 | RO07_01105 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.908 |
| dmdA_2 | ilvD_7 | RO07_00645 | RO07_24340 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.904 |
| dmdA_2 | ilvH | RO07_00645 | RO07_23660 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
| dmdA_2 | mdlC | RO07_00645 | RO07_09555 | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Benzoylformate decarboxylase; Catalyzes the formation of benzaldehyde from benzoylformate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.796 |
| ilvC | dmdA_1 | RO07_23655 | RO07_17445 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.970 |
| ilvC | dmdA_2 | RO07_23655 | RO07_00645 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| ilvC | ilvD_1 | RO07_23655 | RO07_14985 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.983 |
| ilvC | ilvD_2 | RO07_23655 | RO07_14980 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.989 |